Pediatric Sepsis Risk Tool
Phoenix Criteria
SIRS Criteria
LPCH Criteria
Phoenix Criteria
Respiratory (0–3 points)
Select respiratory status:
PaO₂:FiO₂ ≥400 or SpO₂:FiO₂ ≥292
PaO₂:FiO₂ <400 and any support OR SpO₂:FiO₂ <292 with support
PaO₂:FiO₂ 100–200 and IMV OR SpO₂:FiO₂ 148–220 and IMV
PaO₂:FiO₂ <100 and IMV OR SpO₂:FiO₂ <148 and IMV
Cardiovascular (0–6 points)
Select vasoactive support:
No vasoactive medications
1 vasoactive medication
≥2 vasoactive medications
Select lactate level:
Lactate <5 mmol/L
Lactate 5–10.9 mmol/L
Lactate ≥11 mmol/L
Select Age Group:
<1 mo
1–11 mo
1–<2 yr
2–<5 yr
5–<12 yr
12–17 yr
Enter Mean Arterial Pressure (mmHg):
MAP Scoring Table
Age
0 pts
1 pt
2 pts
<1 mo
>30
17–30
<17
1–11 mo
>38
25–38
<25
1–<2 yr
>43
31–43
<31
2–<5 yr
>44
32–44
<32
5–<12 yr
>48
36–48
<36
12–17 yr
>51
38–51
<38
Coagulation (0–2 points)
Select highest scoring abnormality (or none):
All normal: Platelets ≥100k, INR ≤1.3, D-dimer ≤2, Fibrinogen ≥100
1 abnormal value: Platelets <100k, INR >1.3, D-dimer >2, or Fibrinogen <100
2 or more abnormal values
Neurologic (0–2 points)
Select neurological status:
GCS >10; pupils reactive
GCS ≤10
Fixed pupils bilaterally
Calculate Phoenix Score
SIRS Criteria
Temperature <36°C or >38.5°C:
No
Yes
Abnormal heart rate for age:
No
Yes
Abnormal respiratory rate for age:
No
Yes
Abnormal WBC count for age:
No
Yes
SIRS Criteria Table
Age
HR (bpm)
RR (breaths/min)
WBC (×10³/µL)
<1 year
>180 or <90
>34
>34 or <5
1–5 years
>140 or <70
>22
>15.5 or <6
6–12 years
>130 or <60
>18
>13 or <4.5
>12 years
>110 or <55
>14
>11 or <4
Blood Pressure Assessment (Septic Shock Risk)
Select Age Group:
0–1 mo
1–11 mo
1–2 yr
2–5 yr
6–12 yr
13–17 yr
Enter Systolic Blood Pressure (mmHg):
SBP Threshold – Goldstein Criteria (derived from PALS)
Age
SBP (mmHg)
0–1 mo
<65
1–11 mo
<75
1–2 yr
<85
2–5 yr
<90
6–12 yr
<95
13–17 yr
<100
Calculate SIRS Score
Phoenix Criteria
Respiratory (0–3 points)
Select respiratory status:
PaO₂:FiO₂ ≥400 or SpO₂:FiO₂ ≥292
PaO₂:FiO₂ <400 and any support OR SpO₂:FiO₂ <292 with support
PaO₂:FiO₂ 100–200 and IMV OR SpO₂:FiO₂ 148–220 and IMV
PaO₂:FiO₂ <100 and IMV OR SpO₂:FiO₂ <148 and IMV
Cardiovascular (0–6 points)
Select vasoactive support:
No vasoactive medications
1 vasoactive medication
≥2 vasoactive medications
Select lactate level:
Lactate <5 mmol/L
Lactate 5–10.9 mmol/L
Lactate ≥11 mmol/L
Select Age Group:
<1 mo
1–11 mo
1–<2 yr
2–<5 yr
5–<12 yr
12–17 yr
Enter Mean Arterial Pressure (mmHg):
MAP Scoring Table
Age
0 pts
1 pt
2 pts
<1 mo
>30
17–30
<17
1–11 mo
>38
25–38
<25
1–<2 yr
>43
31–43
<31
2–<5 yr
>44
32–44
<32
5–<12 yr
>48
36–48
<36
12–17 yr
>51
38–51
<38
Coagulation (0–2 points)
Select highest scoring abnormality (or none):
All normal: Platelets ≥100k, INR ≤1.3, D-dimer ≤2, Fibrinogen ≥100
1 abnormal value: Platelets <100k, INR >1.3, D-dimer >2, or Fibrinogen <100
2 or more abnormal values
Neurologic (0–2 points)
Select neurological status:
GCS >10; pupils reactive
GCS ≤10
Fixed pupils bilaterally
Calculate Phoenix Score
SIRS Criteria
Temperature <36°C or >38.5°C:
No
Yes
Abnormal heart rate for age:
No
Yes
Abnormal respiratory rate for age:
No
Yes
Abnormal SBP for age:
No
Yes
Vital Signs Concerning for Sepsis – LPCH Sepsis & Septic Shock Pathway
Age
HR
RR
SBP (mmHg)
0–1 M
>205
>60
<60
≥1M – 2M
>205
>60
<70
≥3M –11M
>190
>60
<70
≥12M –23M
>190
>40
<72
≥2Y – 3Y
>140
>40
<74
≥4Y – 5Y
>140
>34
<78
≥6Y – 9Y
>140
>30
<82
≥10Y – 12Y
>100
>30
<90
≥13Y
>100
>16
<90
Blood Pressure Assessment (Septic Shock Risk)
Select Age Group:
0–1 mo
1–11 mo
1–2 yr
2–5 yr
6–12 yr
13–17 yr
Enter Systolic Blood Pressure (mmHg):
Calculate SIRS Score
References
Sanchez-Pinto LN et al. Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024.
Goldstein B et al. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005.
Kache S. LPCH Pediatric Sepsis & Septic Shock Pathway.